2VWE
Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment
Summary for 2VWE
Entry DOI | 10.2210/pdb2vwe/pdb |
Related | 2C7W |
Descriptor | VASCULAR ENDOTHELIAL GROWTH FACTOR B, ANTI-VEGF-B MONOCLONAL ANTIBODY (3 entities in total) |
Functional Keywords | immune system, glycoprotein, cysteine-knot, growth factor, vegf-b, mitogen, secreted, angiogenesis, neutralizing antibody, heparin-binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P49765 |
Total number of polymer chains | 6 |
Total formula weight | 132355.25 |
Authors | Leonard, P.,Scotney, P.D.,Jabeen, T.,Iyer, S.,Fabri, L.J.,Nash, A.D.,Acharya, K.R. (deposition date: 2008-06-23, release date: 2008-11-04, Last modification date: 2023-12-13) |
Primary citation | Leonard, P.,Scotney, P.D.,Jabeen, T.,Iyer, S.,Fabri, L.J.,Nash, A.D.,Acharya, K.R. Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment. J.Mol.Biol., 384:1203-, 2008 Cited by PubMed: 18930733DOI: 10.1016/J.JMB.2008.09.076 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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