2VU9
CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE A BINDING DOMAIN IN COMPLEX WITH GT1B
Summary for 2VU9
Entry DOI | 10.2210/pdb2vu9/pdb |
Related | 1UEE 2VUA 3BTA |
Descriptor | BOTULINUM NEUROTOXIN A HEAVY CHAIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | hydrolase, metalloprotease, neurotoxin, ganglioside, metal-binding, toxin, protease, membrane, receptor, secreted |
Biological source | CLOSTRIDIUM BOTULINUM |
Total number of polymer chains | 1 |
Total formula weight | 53027.84 |
Authors | Stenmark, P.,Dupuy, J.,Stevens, R.C. (deposition date: 2008-05-22, release date: 2008-08-26, Last modification date: 2023-12-13) |
Primary citation | Stenmark, P.,Dupuy, J.,Imamura, A.,Kiso, M.,Stevens, R.C. Crystal Structure of Botulinum Neurotoxin Type a in Complex with the Cell Surface Co-Receptor Gt1B- Insight Into the Toxin-Neuron Interaction. Plos Pathog., 4:E129-, 2008 Cited by PubMed: 18704164DOI: 10.1371/JOURNAL.PPAT.1000129 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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