2VQZ

Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound m7GTP

Summary for 2VQZ

• Entry DOI: 10.2210/pdb2vqz/pdb
• Related: 2JDQ
• Descriptor: POLYMERASE BASIC PROTEIN 2, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: rna-dependent rna polymerase, transcription, pb2 subunit, influenza virus, cap-binding domain
• Biological source: INFLUENZA A VIRUS
• Cellular location: Virion: P31345
• Total number of polymer chains: 5
• Total formula weight: 99280.50

Authors

Guilligay, D.,Tarendeau, F.,Resa-Infante, P.,Coloma, R.,Crepin, T.,Sehr, P.,Lewis, J.,Ruigrok, R.W.H.,Ortin, J.,Hart, D.J.,Cusack, S. (deposition date: 2008-03-21, release date: 2008-05-13, Last modification date: 2011-07-13)

• Primary citation: Guilligay, D.,Tarendeau, F.,Resa-Infante, P.,Coloma, R.,Crepin, T.,Sehr, P.,Lewis, J.,Ruigrok, R.W.H.,Ortin, J.,Hart, D.J.,Cusack, S.; The Structural Basis for CAP Binding by Influenza Virus Polymerase Subunit Pb2.; Nat.Struct.Mol.Biol., 15:500-, 2008; PubMed: 18454157; DOI: 10.1038/NSMB.1421

Experimental method

X-RAY DIFFRACTION (2.3 Å)