2VFZ

CRYSTAL STRUCTURE OF ALPHA-1,3 GALACTOSYLTRANSFERASE (R365K) IN COMPLEX WITH UDP-2F-GALACTOSE

Replaces:  2JCF

Summary for 2VFZ

• Entry DOI: 10.2210/pdb2vfz/pdb
• Related: 1FG5 1G8O 1G93 1GWV 1GWW 1GX0 1GX4 1K4V 1O7O 1O7Q 1VZT 1VZU 1VZX 2JCJ 2JCK 2JCL 2JCO
• Descriptor: N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYL TRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUOROGALACTOSE, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: 3 galactosyltransferase, manganese, transferase, glycoprotein, metal-binding, gt, r365k, alpha-1, membrane, alpha gt, galactose, enzyme mechanism, glycosyltransferase, galactosyltransferase, substrate specificity, signal-anchor, transmembrane, golgi apparatus
• Biological source: BOS TAURUS (BOVINE)
• Cellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P14769
• Total number of polymer chains: 2
• Total formula weight: 69370.76

Authors

Jamaluddin, H.,Tumbale, P.,Withers, S.G.,Acharya, K.R.,Brew, K. (deposition date: 2007-11-06, release date: 2007-11-13, Last modification date: 2024-05-08)

• Primary citation: Jamaluddin, H.,Tumbale, P.,Withers, S.G.,Acharya, K.R.,Brew, K.; Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis; J.Mol.Biol., 369:1270-, 2007; PubMed: 17493636; DOI: 10.1016/J.JMB.2007.04.012

Experimental method

X-RAY DIFFRACTION (2.4 Å)