2V5P
COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II
Summary for 2V5P
Entry DOI | 10.2210/pdb2v5p/pdb |
Related | 1E6F 1GF2 1GP0 1GP3 1GQB 1IGL 1JPL 1JWG 1LF8 2CNJ 2V5N 2V5O |
Descriptor | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, INSULIN-LIKE GROWTH FACTOR II, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | receptor/glycoprotein, cation independent mannose 6-phosphate, membrane, receptor, lysosome, transport, beta barrel, phosphorylation, fibronectin type ii, insulin-like growth factor, receptor-glycoprotein complex, polymorphism, glycoprotein, transmembrane |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 125489.87 |
Authors | Brown, J.,Delaine, C.,Zaccheo, O.J.,Siebold, C.,Gilbert, R.J.,van Boxel, G.,Denley, A.,Wallace, J.C.,Hassan, A.B.,Forbes, B.E.,Jones, E.Y. (deposition date: 2007-07-06, release date: 2007-12-11, Last modification date: 2023-12-13) |
Primary citation | Brown, J.,Delaine, C.,Zaccheo, O.J.,Siebold, C.,Gilbert, R.J.,Van Boxel, G.,Denley, A.,Wallace, J.C.,Hassan, A.B.,Forbes, B.E.,Jones, E.Y. Structure and Functional Analysis of the Igf-II/Igf2R Interaction Embo J., 27:265-, 2008 Cited by PubMed: 18046459DOI: 10.1038/SJ.EMBOJ.7601938 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.1 Å) |
Structure validation
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