2RI7
Crystal structure of PHD finger-linker-bromodomain Y17E mutant from human BPTF in the H3(1-9)K4ME2 bound state
Summary for 2RI7
Entry DOI | 10.2210/pdb2ri7/pdb |
Related | 2F6J 2F6N 2FSA |
Descriptor | Nucleosome-remodeling factor subunit BPTF, histone H3.1, ZINC ION, ... (6 entities in total) |
Functional Keywords | zinc finger, alpha-helical bundle, dimethyl-lysine, bromodomain, chromatin regulator, metal-binding, nucleus, phosphorylation, transcription, transcription regulation, zinc-finger, transcription-nuclear protein complex, transcription/nuclear protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q12830 Nucleus: P68431 |
Total number of polymer chains | 2 |
Total formula weight | 21636.30 |
Authors | Li, H.,Patel, D.J. (deposition date: 2007-10-10, release date: 2007-12-11, Last modification date: 2023-08-30) |
Primary citation | Li, H.,Fischle, W.,Wang, W.,Duncan, E.M.,Liang, L.,Murakami-Ishibe, S.,Allis, C.D.,Patel, D.J. Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger. Mol.Cell, 28:677-691, 2007 Cited by PubMed: 18042461DOI: 10.1016/j.molcel.2007.10.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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