2RG8
Crystal Structure of Programmed for Cell Death 4 Middle MA3 domain
Summary for 2RG8
| Entry DOI | 10.2210/pdb2rg8/pdb |
| Descriptor | Programmed cell death protein 4, CHLORIDE ION, SODIUM ION, ... (4 entities in total) |
| Functional Keywords | ma3 domain, heat repeats, anti-oncogene, apoptosis, cell cycle, cytoplasm, nucleus, phosphorylation, polymorphism, rna-binding, translation |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus : Q53EL6 |
| Total number of polymer chains | 2 |
| Total formula weight | 36143.45 |
| Authors | Garces, R.,Suzuki, C.,Wagner, G. (deposition date: 2007-10-03, release date: 2008-03-04, Last modification date: 2017-10-25) |
| Primary citation | Suzuki, C.,Garces, R.G.,Edmonds, K.A.,Hiller, S.,Hyberts, S.G.,Marintchev, A.,Wagner, G. PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. Proc.Natl.Acad.Sci.Usa, 105:3274-3279, 2008 Cited by PubMed: 18296639DOI: 10.1073/pnas.0712235105 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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