2RFX
Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF
Summary for 2RFX
Entry DOI | 10.2210/pdb2rfx/pdb |
Related | 2bvo 2bvp 2bvq 2hjk 2hjl |
Descriptor | HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, LSSPVTKSF, ... (5 entities in total) |
Functional Keywords | alpha beta sandwich-immunologlobulin like, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P18465 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 44721.70 |
Authors | Archbold, J.K.,Macdonald, W.A.,Rossjohn, J.,McCluskey, J. (deposition date: 2007-10-02, release date: 2008-07-08, Last modification date: 2023-10-25) |
Primary citation | Chessman, D.,Kostenko, L.,Lethborg, T.,Purcell, A.W.,Williamson, N.A.,Chen, Z.,Kjer-Nielsen, L.,Mifsud, N.A.,Tait, B.D.,Holdsworth, R.,Almeida, C.A.,Nolan, D.,Macdonald, W.A.,Archbold, J.K.,Kellerher, A.D.,Marriott, D.,Mallal, S.,Bharadwaj, M.,Rossjohn, J.,McCluskey, J. Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity Immunity, 28:822-832, 2008 Cited by PubMed: 18549801DOI: 10.1016/j.immuni.2008.04.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report