2R0W
PFA2 FAB complexed with Abeta1-8
Summary for 2R0W
Entry DOI | 10.2210/pdb2r0w/pdb |
Related | 2IPT 2IPU 2IQ9 2IQA 2R0W 2R0Z |
Descriptor | IgG2a Fab fragment light chain, IgG2a Fab fragment heavy chain, Fd portion, Amyloid beta peptide fragment, ... (5 entities in total) |
Functional Keywords | immunoglobulin; alzheimer disease; amyloid, immune system |
Biological source | Mus musculus (house mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 3 |
Total formula weight | 49224.90 |
Authors | Gardberg, A.S.,Dealwis, C. (deposition date: 2007-08-21, release date: 2007-10-16, Last modification date: 2017-10-25) |
Primary citation | Gardberg, A.S.,Dice, L.T.,Ou, S.,Rich, R.L.,Helmbrecht, E.,Ko, J.,Wetzel, R.,Myszka, D.G.,Patterson, P.H.,Dealwis, C. Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104:15659-15664, 2007 Cited by PubMed: 17895381DOI: 10.1073/pnas.0705888104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.503 Å) |
Structure validation
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