2QVS
Crystal Structure of Type IIa Holoenzyme of cAMP-dependent Protein Kinase
Summary for 2QVS
Entry DOI | 10.2210/pdb2qvs/pdb |
Related | 1cx4 1rgs 1u7e |
Descriptor | cAMP-dependent protein kinase, alpha-catalytic subunit, cAMP-dependent protein kinase type II-alpha regulatory subunit (3 entities in total) |
Functional Keywords | camp-dependent protein kinase, type iia holoenzyme, isoform diversity, alternative splicing, atp-binding, cytoplasm, lipoprotein, myristate, nucleotide-binding, nucleus, phosphorylation, serine/threonine-protein kinase, transferase, acetylation, camp-binding, transferase-transferase regulator complex, transferase/transferase regulator |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cytoplasm (By similarity): P05132 |
Total number of polymer chains | 2 |
Total formula weight | 75958.33 |
Authors | Wu, J.,Brown, S.H.J.,von Daake, S.,Taylor, S.S. (deposition date: 2007-08-08, release date: 2007-10-23, Last modification date: 2023-08-30) |
Primary citation | Wu, J.,Brown, S.H.J.,von Daake, S.,Taylor, S.S. PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity. Science, 318:274-279, 2007 Cited by PubMed: 17932298DOI: 10.1126/science.1146447 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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