2QS3
Crystal structure of the GluR5 ligand binding core dimer in complex with UBP316 at 1.76 Angstroms resolution
Summary for 2QS3
Entry DOI | 10.2210/pdb2qs3/pdb |
Related | 1TXF 2F34 2F35 2F36 2QS1 2QS2 2QS4 |
Descriptor | Glutamate receptor, ionotropic kainate 1, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | membrane protein, cell junction, glycoprotein, ion transport, ionic channel, phosphorylation, postsynaptic cell membrane, receptor, rna editing, synapse, transmembrane, transport |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P22756 |
Total number of polymer chains | 2 |
Total formula weight | 59829.42 |
Authors | Alushin, G.M.,Jane, D.E.,Mayer, M.L. (deposition date: 2007-07-30, release date: 2008-08-05, Last modification date: 2023-08-30) |
Primary citation | Dargan, S.L.,Clarke, V.R.,Alushin, G.M.,Sherwood, J.L.,Nistico, R.,Bortolotto, Z.A.,Ogden, A.M.,Bleakman, D.,Doherty, A.J.,Lodge, D.,Mayer, M.L.,Fitzjohn, S.M.,Jane, D.E.,Collingridge, G.L. ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function. Neuropharmacology, 56:121-130, 2009 Cited by PubMed: 18789344DOI: 10.1016/j.neuropharm.2008.08.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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