2QRZ
Cdc42 bound to GMP-PCP: Induced Fit by Effector is Required
Summary for 2QRZ
Entry DOI | 10.2210/pdb2qrz/pdb |
Descriptor | Cell division control protein 42 homolog precursor, MAGNESIUM ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | g-domain fold, g protein, gtpase, alternative splicing, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, cell cycle |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953 |
Total number of polymer chains | 2 |
Total formula weight | 43301.62 |
Authors | Phillips, M.J.,Calero, G.,Chan, B.,Cerione, R.A. (deposition date: 2007-07-30, release date: 2008-03-18, Last modification date: 2011-07-13) |
Primary citation | Phillips, M.J.,Calero, G.,Chan, B.,Ramachandran, S.,Cerione, R.A. Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42. J.Biol.Chem., 283:14153-14164, 2008 Cited by PubMed: 18348980DOI: 10.1074/jbc.M706271200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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