2QOH
Crystal Structure of Abl kinase bound with PPY-A
Summary for 2QOH
Entry DOI | 10.2210/pdb2qoh/pdb |
Related | 2Z60 |
Descriptor | Proto-oncogene tyrosine-protein kinase ABL1, 5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE (3 entities in total) |
Functional Keywords | abl, kinase, inhibitor, transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm, cytoskeleton: P00520 |
Total number of polymer chains | 2 |
Total formula weight | 67228.77 |
Authors | Zhou, T.,Dalgarno, D.,Zhu, X. (deposition date: 2007-07-20, release date: 2007-09-18, Last modification date: 2023-10-25) |
Primary citation | Zhou, T.,Parillon, L.,Li, F.,Wang, Y.,Keats, J.,Lamore, S.,Xu, Q.,Shakespeare, W.,Dalgarno, D.,Zhu, X. Crystal Structure of the T315I Mutant of Abl Kinase Chem.Biol.Drug Des., 70:171-181, 2007 Cited by PubMed: 17718712DOI: 10.1111/j.1747-0285.2007.00556.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report