2QOF

Human EphA3 kinase and juxtamembrane region, Y596F mutant

Summary for 2QOF

Entry DOI	10.2210/pdb2qof/pdb
Related	2GSF 2QO2 2QO7 2QO9 2QOB 2QOC 2QOD 2QOI 2QOK 2QOL 2QON 2QOO 2QOQ
Descriptor	Ephrin receptor, BETA-MERCAPTOETHANOL (3 entities in total)
Functional Keywords	receptor tyrosine kinase, juxtamembrane segment, structural genomics, structural genomics consortium, sgc, atp-binding, nucleotide-binding, phosphorylation, transferase, transmembrane, tyrosine-protein kinase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	42026.00
Authors	Davis, T.,Walker, J.R.,Newman, E.M.,Mackenzie, F.,Butler-Cole, C.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-07-20, release date: 2007-08-21, Last modification date: 2023-08-30)
Primary citation	Davis, T.L.,Walker, J.R.,Loppnau, P.,Butler-Cole, C.,Allali-Hassani, A.,Dhe-Paganon, S. Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3). Structure, 16:873-884, 2008 Cited by PubMed: 18547520 DOI: 10.1016/j.str.2008.03.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation