2QDJ
Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
Summary for 2QDJ
Entry DOI | 10.2210/pdb2qdj/pdb |
Descriptor | Retinoblastoma-associated protein (2 entities in total) |
Functional Keywords | cyclin fold, cyclin wedge, antitumor protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P06400 |
Total number of polymer chains | 1 |
Total formula weight | 35427.97 |
Authors | Hassler, M.,Mittnacht, S.,Pearl, L.H. (deposition date: 2007-06-21, release date: 2008-01-22, Last modification date: 2011-07-13) |
Primary citation | Hassler, M.,Singh, S.,Yue, W.W.,Luczynski, M.,Lakbir, R.,Sanchez-Sanchez, F.,Bader, T.,Pearl, L.H.,Mittnacht, S. Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Mol.Cell, 28:371-385, 2007 Cited by PubMed: 17996702DOI: 10.1016/j.molcel.2007.08.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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