2Q8M
T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound
Summary for 2Q8M
Entry DOI | 10.2210/pdb2q8m/pdb |
Related | 2GQ1 2OWZ 2OX3 |
Descriptor | Fructose-bisphosphatase, 6-O-phosphono-beta-D-glucopyranose, 1,6-di-O-phosphono-beta-D-fructofuranose, ... (7 entities in total) |
Functional Keywords | glycolysis, gluconeogenesis, bacteria, carbohydrate metabolism, diabetes, protein-protein interactions, proteobacteria, gram-negative, protein crystallography, heterotrophic, allosteric regulation, hydrolase |
Biological source | Shigella boydii |
Total number of polymer chains | 2 |
Total formula weight | 76160.86 |
Authors | Hines, J.K.,Kruesel, C.E.,Fromm, H.J.,Honzatko, R.B. (deposition date: 2007-06-11, release date: 2007-06-19, Last modification date: 2023-11-15) |
Primary citation | Hines, J.K.,Kruesel, C.E.,Fromm, H.J.,Honzatko, R.B. Structure of Inhibited Fructose-1,6-bisphosphatase from Escherichia coli: DISTINCT ALLOSTERIC INHIBITION SITES FOR AMP AND GLUCOSE 6-PHOSPHATE AND THE CHARACTERIZATION OF A GLUCONEOGENIC SWITCH. J.Biol.Chem., 282:24697-24706, 2007 Cited by PubMed: 17567577DOI: 10.1074/jbc.M703580200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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