2Q7L
The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and a TIF2 box3 Coactivator Peptide 740-753
Summary for 2Q7L
Entry DOI | 10.2210/pdb2q7l/pdb |
Descriptor | Androgen receptor, Nuclear receptor coactivator 2, TESTOSTERONE, ... (5 entities in total) |
Functional Keywords | androgen receptor prostate cancer mutant h874y ligand binding domain, testosterone, tif2 boxiii coactivator peptide, hormone |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P10275 Q15596 |
Total number of polymer chains | 2 |
Total formula weight | 32121.57 |
Authors | Gampe, R.T. (deposition date: 2007-06-07, release date: 2007-07-24, Last modification date: 2024-02-21) |
Primary citation | Askew, E.B.,Gampe, R.T.,Stanley, T.B.,Faggart, J.L.,Wilson, E.M. Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone. J.Biol.Chem., 282:25801-25816, 2007 Cited by PubMed: 17591767DOI: 10.1074/jbc.M703268200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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