2Q6N

Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole

Summary for 2Q6N

• Entry DOI: 10.2210/pdb2q6n/pdb
• Related: 1PO5 1SUO 2BDM
• Descriptor: Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 1-(4-CHLOROPHENYL)-1H-IMIDAZOLE (3 entities in total)
• Functional Keywords: p450, monooxygenase, oxidoreductase, membrane protein, cyp 2b4, cyp lm2
• Biological source: Oryctolagus cuniculus (rabbit)
• Cellular location: Endoplasmic reticulum membrane; Peripheral membrane protein: P00178
• Total number of polymer chains: 7
• Total formula weight: 386683.33

Authors

Zhao, Y.,Sun, L.,Muralidhara, B.K.,Kumar, S.,White, M.A.,Stout, C.D.,Halpert, J.R. (deposition date: 2007-06-05, release date: 2007-11-06, Last modification date: 2023-08-30)

• Primary citation: Zhao, Y.,Sun, L.,Muralidhara, B.K.,Kumar, S.,White, M.A.,Stout, C.D.,Halpert, J.R.; Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4.; Biochemistry, 46:11559-11567, 2007; PubMed: 17887776; DOI: 10.1021/bi7011614

Experimental method

X-RAY DIFFRACTION (3.2 Å)