2PH9

Galanthamine bound to an ACh-binding Protein

Summary for 2PH9

Entry DOI	10.2210/pdb2ph9/pdb
Related	2PGZ
Descriptor	Soluble acetylcholine receptor, (-)-GALANTHAMINE, TETRAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	non-competitive inhibitors, nicotinic acetylcholine receptor, acetylcholine-binding protein, benzodiazepine, galanthamine, choline-binding protein
Biological source	Aplysia californica (California sea hare)
Total number of polymer chains	5
Total formula weight	132404.17
Authors	Hansen, S.B.,Taylor, P. (deposition date: 2007-04-10, release date: 2007-07-03, Last modification date: 2023-08-30)
Primary citation	Hansen, S.B.,Taylor, P. Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors. J.Mol.Biol., 369:895-901, 2007 Cited by PubMed: 17481657 DOI: 10.1016/j.jmb.2007.03.067 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.88 Å)

Structure validation