2P7Q

Crystal structure of E126Q mutant of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes complexed with MN(II) and 1S,2S-dihydroxypropylphosphonic acid

Summary for 2P7Q

Entry DOI	10.2210/pdb2p7q/pdb
Related	2P7K 2P7L 2P7M 2P7O 2P7P
Descriptor	Glyoxalase family protein, MANGANESE (II) ION, [(1S,2S)-1,2-DIHYDROXYPROPYL]PHOSPHONIC ACID, ... (4 entities in total)
Functional Keywords	fosfomycin resistance protein, mn binding, antibiotic resistance, metal binding protein, hydrolase
Biological source	Listeria monocytogenes
Total number of polymer chains	6
Total formula weight	94803.78
Authors	Fillgrove, K.L.,Pakhomova, S.,Schaab, M.,Newcomer, M.E.,Armstrong, R.N. (deposition date: 2007-03-20, release date: 2007-07-17, Last modification date: 2023-08-30)
Primary citation	Fillgrove, K.L.,Pakhomova, S.,Schaab, M.R.,Newcomer, M.E.,Armstrong, R.N. Structure and Mechanism of the Genomically Encoded Fosfomycin Resistance Protein, FosX, from Listeria monocytogenes. Biochemistry, 46:8110-8120, 2007 Cited by PubMed: 17567049 DOI: 10.1021/bi700625p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation