2P53

Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D273N mutant complexed with N-acetyl phosphonamidate-d-glucosamine-6-phosphate

Summary for 2P53

• Entry DOI: 10.2210/pdb2p53/pdb
• Related: 1YMY 2P50
• Descriptor: N-acetylglucosamine-6-phosphate deacetylase, ZINC ION, 2-deoxy-2-{[(S)-hydroxy(methyl)phosphoryl]amino}-6-O-phosphono-alpha-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: n-acetyl-d-glucosamine-6-phosphate deacetylase, aminohydrolase, (beta/alpha)8-barrel, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 82787.06

Authors

Fedorov, A.A.,Fedorov, E.V.,Hall, R.S.,Raushel, F.M.,Almo, S.C. (deposition date: 2007-03-14, release date: 2007-07-24, Last modification date: 2023-08-30)

• Primary citation: Hall, R.S.,Brown, S.,Fedorov, A.A.,Fedorov, E.V.,Xu, C.,Babbitt, P.C.,Almo, S.C.,Raushel, F.M.; Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase.; Biochemistry, 46:7953-7962, 2007; PubMed: 17567048; DOI: 10.1021/bi700544c

Experimental method

X-RAY DIFFRACTION (2.1 Å)