2OUO
Crystal Structure of the Bromo domain 2 in human Bromodomain Containing Protein 4 (BRD4)
Summary for 2OUO
Entry DOI | 10.2210/pdb2ouo/pdb |
Related | 2OSS |
Descriptor | Bromodomain-containing protein 4, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | brd4, bromodomain containing protein 4, structural genomics consortium, sgc, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O60885 |
Total number of polymer chains | 1 |
Total formula weight | 15246.54 |
Authors | Filippakopoulos, P.,Keates, T.,Savitsky, P.,Burgess, N.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-02-12, release date: 2007-02-27, Last modification date: 2023-08-30) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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