2OSM
Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study
Summary for 2OSM
Entry DOI | 10.2210/pdb2osm/pdb |
Related | 2OSF |
Descriptor | Carbonic anhydrase 2, ZINC ION, 2-MERCAPTOPHENOL, ... (4 entities in total) |
Functional Keywords | human carbonic anhydrase ii, 2-hydroxythiophenol, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29349.45 |
Authors | Albert, A.B.,Caroli, G.,Govindasamy, L.,Agbandje-Mckenna, M.,McKenna, R.,Tripp, B.C. (deposition date: 2007-02-06, release date: 2008-02-12, Last modification date: 2023-08-30) |
Primary citation | Barrese, A.A.,Genis, C.,Fisher, S.Z.,Orwenyo, J.N.,Kumara, M.T.,Dutta, S.K.,Phillips, E.,Kiddle, J.J.,Tu, C.,Silverman, D.N.,Govindasamy, L.,Agbandje-McKenna, M.,McKenna, R.,Tripp, B.C. Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study. Biochemistry, 47:3174-3184, 2008 Cited by PubMed: 18266323DOI: 10.1021/bi702385k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report