2OKJ
The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67)
Summary for 2OKJ
Entry DOI | 10.2210/pdb2okj/pdb |
Related | 2OKK |
Descriptor | Glutamate decarboxylase 1, GAMMA-AMINO-BUTANOIC ACID, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, ... (4 entities in total) |
Functional Keywords | plp-dependent decarboxylase, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 115307.78 |
Authors | Buckle, A.M.,Fenalti, G.,Law, R.H.P.,Whisstock, J.C. (deposition date: 2007-01-17, release date: 2007-03-27, Last modification date: 2023-11-15) |
Primary citation | Fenalti, G.,Law, R.H.P.,Buckle, A.M.,Langendorf, C.,Tuck, K.,Rosado, C.J.,Faux, N.G.,Mahmood, K.,Hampe, C.S.,Banga, J.P.,Wilce, M.,Schmidberger, J.,Rossjohn, J.,El-Kabbani, O.,Pike, R.N.,Smith, A.I.,Mackay, I.R.,Rowley, M.J.,Whisstock, J.C. GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat.Struct.Mol.Biol., 14:280-286, 2007 Cited by PubMed: 17384644DOI: 10.1038/nsmb1228 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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