2OIT

Crystal Structure of the N-terminal Domain of the Human Proto-oncogene Nup214/CAN

Summary for 2OIT

Entry DOI	10.2210/pdb2oit/pdb
Descriptor	Nucleoporin 214kDa, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total)
Functional Keywords	nh2 terminal domain of nup214/can, beta-propeller, mrna export, npc assembly, leukemia, nup214/can fusion, dbp5/ddx19, oncoprotein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	48313.53
Authors	Napetschnig, J.,Blobel, G.,Hoelz, A. (deposition date: 2007-01-11, release date: 2007-02-06, Last modification date: 2023-12-27)
Primary citation	Napetschnig, J.,Blobel, G.,Hoelz, A. Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN. Proc.Natl.Acad.Sci.Usa, 104:1783-1788, 2007 Cited by PubMed: 17264208 DOI: 10.1073/pnas.0610828104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation