2ODQ

Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement

Summary for 2ODQ

• Entry DOI: 10.2210/pdb2odq/pdb
• Related: 2ODP
• Related PRD ID: PRD_900017
• Descriptor: Complement C2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: complement component c2a, c3/c5 convertase, complement serine protease, human complement system, glycoprotein, sp, vwfa, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P06681
• Total number of polymer chains: 1
• Total formula weight: 59157.01

Authors

Narayana, S.V.L.,Krishnan, V. (deposition date: 2006-12-25, release date: 2007-02-06, Last modification date: 2023-10-25)

• Primary citation: Krishnan, V.,Xu, Y.,Macon, K.,Volanakis, J.E.,Narayana, S.V.; The crystal structure of c2a, the catalytic fragment of classical pathway c3 and c5 convertase of human complement.; J.Mol.Biol., 367:224-233, 2007; PubMed: 17234210; DOI: 10.1016/j.jmb.2006.12.039

Experimental method

X-RAY DIFFRACTION (2.3 Å)