2NV6
Mycobacterium tuberculosis InhA (S94A) bound with INH-NAD adduct
Summary for 2NV6
| Entry DOI | 10.2210/pdb2nv6/pdb |
| Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH, ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE (3 entities in total) |
| Functional Keywords | inha, s94a, tuberculosis, isoniazid, oxidoreductase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 29146.08 |
| Authors | Wang, F.,Sacchettini, J.C. (deposition date: 2006-11-10, release date: 2006-11-21, Last modification date: 2023-08-30) |
| Primary citation | Vilcheze, C.,Wang, F.,Arai, M.,Hazbon, M.H.,Colangeli, R.,Kremer, L.,Weisbrod, T.R.,Alland, D.,Sacchettini, J.C.,Jacobs Jr., W.R. Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid. NAT.MED. (N.Y.), 12:1027-1029, 2006 Cited by PubMed: 16906155DOI: 10.1038/nm1466 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report
