2NGR
TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
Summary for 2NGR
Entry DOI | 10.2210/pdb2ngr/pdb |
Descriptor | PROTEIN (GTP BINDING PROTEIN (G25K)), PROTEIN (GTPASE ACTIVATING PROTEIN (RHG)), MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | transition state, g-protein, gap, cdc42, alf3., hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P60953 Cytoplasm: Q07960 |
Total number of polymer chains | 2 |
Total formula weight | 48286.35 |
Authors | Nassar, N.,Hoffman, G.,Clardy, J.,Cerione, R. (deposition date: 1998-07-31, release date: 1999-01-06, Last modification date: 2023-08-30) |
Primary citation | Nassar, N.,Hoffman, G.R.,Manor, D.,Clardy, J.C.,Cerione, R.A. Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nat.Struct.Biol., 5:1047-1052, 1998 Cited by PubMed: 9846874DOI: 10.1038/4156 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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