2N0W
Mdmx-SJ212
Summary for 2N0W
Entry DOI | 10.2210/pdb2n0w/pdb |
Related | 2N06 2N0U 2N14 |
NMR Information | BMRB: 25538 |
Descriptor | Protein Mdm4, 4-({(4S,5R)-4-(5-bromo-2-fluorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one (2 entities in total) |
Functional Keywords | mdmx, negative regulators of p53, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O15151 |
Total number of polymer chains | 1 |
Total formula weight | 10804.83 |
Authors | Grace, C.R.,Kriwacki, R.W. (deposition date: 2015-03-17, release date: 2016-01-27, Last modification date: 2024-05-01) |
Primary citation | Grace, C.R.,Ban, D.,Min, J.,Mayasundari, A.,Min, L.,Finch, K.E.,Griffiths, L.,Bharatham, N.,Bashford, D.,Kiplin Guy, R.,Dyer, M.A.,Kriwacki, R.W. Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428:1290-1303, 2016 Cited by PubMed: 26812210DOI: 10.1016/j.jmb.2016.01.016 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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