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2MZX

CCR5-ECL2 helical structure, residues Q186-T195

Summary for 2MZX
Entry DOI10.2210/pdb2mzx/pdb
NMR InformationBMRB: 25505
DescriptorC-C chemokine receptor type 5 (1 entity in total)
Functional Keywordssignaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane ; Multi-pass membrane protein : P51681
Total number of polymer chains1
Total formula weight1390.52
Authors
Abayev, M.,Anglister, J. (deposition date: 2015-02-26, release date: 2015-04-22, Last modification date: 2023-06-14)
Primary citationAbayev, M.,Moseri, A.,Tchaicheeyan, O.,Kessler, N.,Arshava, B.,Naider, F.,Scherf, T.,Anglister, J.
An extended CCR5 ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions.
Febs J., 282:1906-1921, 2015
Cited by
PubMed: 25703038
DOI: 10.1111/febs.13243
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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