2MNX

Major groove orientation of the (2S)-N6-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA adduct induced by 1,2-epoxy-3-butene

Summary for 2MNX

• Entry DOI: 10.2210/pdb2mnx/pdb
• NMR Information: BMRB: 19912
• Descriptor: 5'-D(*CP*GP*GP*AP*CP*(6HB)P*AP*GP*AP*AP*G)-3', 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3' (2 entities in total)
• Functional Keywords: b-form, 11-mer, dna
• Total number of polymer chains: 2
• Total formula weight: 6777.50

Authors

Kowal, E.A.,Kotapati, S.,Turo, M.,Tretyakova, N.,Stone, M.P. (deposition date: 2014-04-16, release date: 2014-10-08, Last modification date: 2024-05-01)

• Primary citation: Kowal, E.A.,Wickramaratne, S.,Kotapati, S.,Turo, M.,Tretyakova, N.,Stone, M.P.; Major Groove Orientation of the (2S)-N(6)-(2-Hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA Adduct Induced by 1,2-Epoxy-3-butene.; Chem.Res.Toxicol., 27:1675-1686, 2014; PubMed: 25238403; DOI: 10.1021/tx500159w

Experimental method

SOLUTION NMR