2MLR

Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Alpha-face

Summary for 2MLR

Entry DOI	10.2210/pdb2mlr/pdb
Related	2MLS 2POJ
Descriptor	Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywords	membrane-binding of soluble metalloproteinase mmp-12, catalytic domain, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space, extracellular matrix : P39900
Total number of polymer chains	1
Total formula weight	103295.93
Authors	Koppisetti, R.K.,Fulcher, Y.G.,Prior, S.H.,Lenoir, M.,Overduin, M.,Van Doren, S.R. (deposition date: 2014-03-04, release date: 2014-12-03, Last modification date: 2014-12-10)
Primary citation	Koppisetti, R.K.,Fulcher, Y.G.,Jurkevich, A.,Prior, S.H.,Xu, J.,Lenoir, M.,Overduin, M.,Van Doren, S.R. Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12. Nat Commun, 5:5552-5552, 2014 Cited by PubMed: 25412686 DOI: 10.1038/ncomms6552 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation