2ME1
HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle
Summary for 2ME1
Entry DOI | 10.2210/pdb2me1/pdb |
Related | 2ME2 2ME3 2ME4 2PV6 |
NMR Information | BMRB: 19512 |
Descriptor | Gp41 (1 entity in total) |
Functional Keywords | mper, viral fusion, helix-hinge-helix, membrane protein |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578 |
Total number of polymer chains | 1 |
Total formula weight | 3455.95 |
Authors | Sun, Z.J.,Wagner, G.,Reinherz, E.L.,Kim, M.,Song, L.,Choi, J.,Cheng, Y.,Chowdhury, B.,Bellot, G.,Shih, W. (deposition date: 2013-09-20, release date: 2013-10-09, Last modification date: 2024-05-15) |
Primary citation | Sun, Z.Y.,Cheng, Y.,Kim, M.,Song, L.,Choi, J.,Kudahl, U.J.,Brusic, V.,Chowdhury, B.,Yu, L.,Seaman, M.S.,Bellot, G.,Shih, W.M.,Wagner, G.,Reinherz, E.L. Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426:1095-1108, 2014 Cited by PubMed: 24075869DOI: 10.1016/j.jmb.2013.09.030 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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