2MDJ

Solution structure of WW domain with polyproline stretch (PP2WW) of HYPB

Summary for 2MDJ

• Entry DOI: 10.2210/pdb2mdj/pdb
• Related: 2MDC 2MDI
• NMR Information: BMRB: 19488
• Descriptor: Histone-lysine N-methyltransferase SETD2 (1 entity in total)
• Functional Keywords: ww domain, hypb, polyproline, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Probable): Q9BYW2
• Total number of polymer chains: 1
• Total formula weight: 6336.02

Authors

Gao, Y.,Hu, H. (deposition date: 2013-09-11, release date: 2014-09-10, Last modification date: 2024-05-15)

• Primary citation: Gao, Y.G.,Yang, H.,Zhao, J.,Jiang, Y.J.,Hu, H.Y.; Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin; Structure, 22:378-386, 2014; PubMed: 24412394; DOI: 10.1016/j.str.2013.12.005

Experimental method

SOLUTION NMR