2LZK
NMR solution structure of an N2-guanine DNA adduct derived from the potent tumorigen dibenzo[a,l]pyrene: Intercalation from the minor groove with ruptured Watson-Crick base pairing
Summary for 2LZK
Entry DOI | 10.2210/pdb2lzk/pdb |
NMR Information | BMRB: 18762 |
Descriptor | DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'), (11S,12S,13S)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol (3 entities in total) |
Functional Keywords | 14r (+)-trans-anti-db[a, l]p-n2-dg, dna adduct, dna |
Total number of polymer chains | 2 |
Total formula weight | 7062.79 |
Authors | Tang, Y.,Liu, Z.,Ding, S.,Lin, C.H.,Cai, Y.,Rodriguez, F.A.,Sayer, J.M.,Jerina, D.M.,Amin, S.,Broyde, S.,Geacintov, N.E. (deposition date: 2012-10-04, release date: 2012-11-21, Last modification date: 2024-05-15) |
Primary citation | Tang, Y.,Liu, Z.,Ding, S.,Lin, C.H.,Cai, Y.,Rodriguez, F.A.,Sayer, J.M.,Jerina, D.M.,Amin, S.,Broyde, S.,Geacintov, N.E. Nuclear Magnetic Resonance Solution Structure of an N(2)-Guanine DNA Adduct Derived from the Potent Tumorigen Dibenzo[a,l]pyrene: Intercalation from the Minor Groove with Ruptured Watson-Crick Base Pairing. Biochemistry, 51:9751-9762, 2012 Cited by PubMed: 23121427DOI: 10.1021/bi3013577 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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