2LR1
Structural Mechanism for Bax Inhibition by Cytomegalovirus Protein vMIA
Summary for 2LR1
Entry DOI | 10.2210/pdb2lr1/pdb |
Related | 1F16 |
NMR Information | BMRB: 18340 |
Descriptor | Apoptosis regulator BAX, Immediate early glycoprotein (2 entities in total) |
Functional Keywords | apoptosis-signaling protein complex, apoptosis/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform Alpha: Mitochondrion membrane; Single-pass membrane protein. Isoform Beta: Cytoplasm. Isoform Gamma: Cytoplasm. Isoform Delta: Cytoplasm : Q07812 Isoform gpUL37: Host endoplasmic reticulum membrane ; Single-pass membrane protein . Isoform vMIA: Host mitochondrion membrane ; Single-pass membrane protein . Isoform pUL37m: Host mitochondrion membrane ; Single-pass membrane protein : P16778 |
Total number of polymer chains | 2 |
Total formula weight | 23936.64 |
Authors | |
Primary citation | Ma, J.,Edlich, F.,Bermejo, G.A.,Norris, K.L.,Youle, R.J.,Tjandra, N. Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA. Proc.Natl.Acad.Sci.USA, 109:20901-20906, 2012 Cited by PubMed: 23213219DOI: 10.1073/pnas.1217094110 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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