2LI8
The solution structure of the Lin28-ZnF domains bound to AGGAGAU of pre-let-7 miRNA
Summary for 2LI8
Entry DOI | 10.2210/pdb2li8/pdb |
Related | 2CQF |
NMR Information | BMRB: 17883 |
Descriptor | Protein lin-28 homolog A, RNA (5'-R(*AP*GP*GP*AP*GP*AP*U)-3'), ZINC ION (3 entities in total) |
Functional Keywords | zinc finger, micro rna, transcription-rna complex, transcription/rna |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9H9Z2 |
Total number of polymer chains | 2 |
Total formula weight | 10448.64 |
Authors | Allain, F.H.-T.,Loughlin, F.E. (deposition date: 2011-08-25, release date: 2011-12-07, Last modification date: 2024-05-01) |
Primary citation | Loughlin, F.E.,Gebert, L.F.,Towbin, H.,Brunschweiger, A.,Hall, J.,Allain, F.H. Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28. Nat.Struct.Mol.Biol., 19:84-89, 2011 Cited by PubMed: 22157959DOI: 10.1038/nsmb.2202 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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