2L5S
Solution structure of the extracellular domain of the TGF-beta type I receptor
Summary for 2L5S
Entry DOI | 10.2210/pdb2l5s/pdb |
Descriptor | TGF-beta receptor type-1 (1 entity in total) |
Functional Keywords | alk5, transforming growth factor beta, type i receptor, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P36897 |
Total number of polymer chains | 1 |
Total formula weight | 9472.83 |
Authors | Zuniga, J.E.,Ilangovan, U.,Pardeep, M.,Hinck, C.,Huang, T. (deposition date: 2010-11-04, release date: 2011-10-26) |
Primary citation | Zuniga, J.E.,Ilangovan, U.,Mahlawat, P.,Hinck, C.S.,Huang, T.,Groppe, J.C.,McEwen, D.G.,Hinck, A.P. The TbetaR-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding J.Mol.Biol., 412:601-618, 2011 Cited by PubMed: 21821041DOI: 10.1016/j.jmb.2011.07.046 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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