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2L3Y

Solution structure of mouse IL-6

Summary for 2L3Y
Entry DOI10.2210/pdb2l3y/pdb
DescriptorInterleukin-6 (1 entity in total)
Functional Keywordscytokine, interleukin, signaling, gp-130, transcription
Biological sourceMus musculus (mouse)
Cellular locationSecreted: P08505
Total number of polymer chains1
Total formula weight21922.92
Authors
Veverka, V.,Redpath, N.T.,Carrington, B.,Muskett, F.W.,Taylor, R.J.,Henry, A.J.,Carr, M.D. (deposition date: 2010-09-25, release date: 2011-09-28, Last modification date: 2013-01-02)
Primary citationVeverka, V.,Baker, T.,Redpath, N.T.,Carrington, B.,Muskett, F.W.,Taylor, R.J.,Lawson, A.D.,Henry, A.J.,Carr, M.D.
Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.
J.Biol.Chem., 287:40043-40050, 2012
Cited by
PubMed: 23027872
DOI: 10.1074/jbc.M112.405597
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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