2L14
Structure of CBP nuclear coactivator binding domain in complex with p53 TAD
Summary for 2L14
| Entry DOI | 10.2210/pdb2l14/pdb |
| NMR Information | BMRB: 17073 |
| Descriptor | CREB-binding protein, Cellular tumor antigen p53 (2 entities in total) |
| Functional Keywords | p53, cbp, p300, tad, protein binding |
| Biological source | Mus musculus (mouse) More |
| Cellular location | Cytoplasm (By similarity): P45481 Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 |
| Total number of polymer chains | 2 |
| Total formula weight | 12142.66 |
| Authors | Lee, C.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E. (deposition date: 2010-07-22, release date: 2010-11-03, Last modification date: 2011-07-13) |
| Primary citation | Lee, C.W.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E. Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein. Biochemistry, 49:9964-9971, 2010 Cited by PubMed: 20961098DOI: 10.1021/bi1012996 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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