2KWG
Solution structure of a fully modified 2'-F/2'-OMe siRNA construct
Summary for 2KWG
Entry DOI | 10.2210/pdb2kwg/pdb |
NMR Information | BMRB: 16852 |
Descriptor | 5'-R(*(GF2)P*(OMG)P*(GF2)P*(OMU)P*(AF2)P*(A2M)P*(AF2)P*(OMU)P*(AF2)P*(OMC)P*(AF2)P*(OMU)P*(UFT)P*(OMC)P*(UFT)P*(OMU)P*(CFZ)P*(A2M)P*(UFT)P*(OMU)P*(UFT))-3', 5'-R(P*(A2M)P*(UFT)P*(OMG)P*(AF2)P*(A2M)P*(GF2)P*(A2M)P*(AF2)P*(OMU)P*(GF2)P*(OMU)P*(AF2)P*(OMU)P*(UFT)P*(OMU)P*(AF2)P*(OMC)P*(CFZ)P*(OMC)P*(UFT)P*(OMU))-3' (2 entities in total) |
Functional Keywords | sirna, 2'-fluoro, 2'-o-methyl, rna |
Total number of polymer chains | 2 |
Total formula weight | 13633.28 |
Authors | Podbevsek, P.,Bhat, B.,Plavec, J. (deposition date: 2010-04-09, release date: 2010-07-21, Last modification date: 2024-05-01) |
Primary citation | Podbevsek, P.,Allerson, C.R.,Bhat, B.,Plavec, J. Solution-state structure of a fully alternately 2'-F/2'-OMe modified 42-nt dimeric siRNA construct. Nucleic Acids Res., 38:7298-7307, 2010 Cited by PubMed: 20624819DOI: 10.1093/nar/gkq621 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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