2KES

Solution Structure of the Coiled-coil Domain of Synphilin-1

Summary for 2KES

• Entry DOI: 10.2210/pdb2kes/pdb
• NMR Information: BMRB: 16156
• Descriptor: Synphilin-1 (1 entity in total)
• Functional Keywords: synphillin, coiled-coil, ank repeat, disease mutation, parkinson disease, phosphoprotein, polymorphism, ubl conjugation, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q9Y6H5
• Total number of polymer chains: 1
• Total formula weight: 5371.14

Authors

Xie, Y.Y.,Zhou, C.J.,Zhou, Z.R.,Hu, H.Y. (deposition date: 2009-02-02, release date: 2009-02-24, Last modification date: 2022-03-16)

• Primary citation: Xie, Y.Y.,Zhou, C.J.,Zhou, Z.R.,Hong, J.,Che, M.X.,Fu, Q.S.,Song, A.X.,Lin, D.H.,Hu, H.Y.; Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication.; Faseb J., 24:196-205, 2010; PubMed: 19762560; DOI: 10.1096/fj.09-133082

Experimental method

SOLUTION NMR