2KE3
PC1/3 DCSG sorting domain in CHAPS
Summary for 2KE3
| Entry DOI | 10.2210/pdb2ke3/pdb |
| Descriptor | Neuroendocrine convertase 1 (1 entity in total) |
| Functional Keywords | secretory granules, prohormone convertase, calcium, cleavage on pair of basic residues, cytoplasmic vesicle, glycoprotein, hydrolase, protease, serine protease, zymogen |
| Biological source | Mus musculus (Mouse) |
| Cellular location | Cytoplasmic vesicle, secretory vesicle: P63239 |
| Total number of polymer chains | 1 |
| Total formula weight | 5131.60 |
| Authors | Dikeakos, J.D.,Di Lello, P.,Lacombe, M.J.,Ghirlando, R.,Legault, P.,Reudelhuber, T.L.,Omichinski, J.G. (deposition date: 2009-01-22, release date: 2009-04-14, Last modification date: 2022-03-16) |
| Primary citation | Dikeakos, J.D.,Di Lello, P.,Lacombe, M.J.,Ghirlando, R.,Legault, P.,Reudelhuber, T.L.,Omichinski, J.G. Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease Proc.Natl.Acad.Sci.USA, 106:7408-7413, 2009 Cited by PubMed: 19376969DOI: 10.1073/pnas.0809576106 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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