2JX0
The paxillin-binding domain (PBD) of G Protein Coupled Receptor (GPCR)-kinase (GRK) interacting protein 1 (GIT1)
Summary for 2JX0
| Entry DOI | 10.2210/pdb2jx0/pdb |
| Descriptor | ARF GTPase-activating protein GIT1 (1 entity in total) |
| Functional Keywords | paxillin binding domain homologue, ank repeat, cytoplasm, gtpase activation, metal-binding, phosphorylation, zinc, zinc-finger, cell adhesion, signaling protein |
| Biological source | Rattus norvegicus (Norway rat) |
| Cellular location | Cytoplasm (By similarity): Q9Z272 |
| Total number of polymer chains | 1 |
| Total formula weight | 15029.24 |
| Authors | Zhang, Z.,Guibao, C.D.,Simmerman, J.A.,Zheng, J. (deposition date: 2007-11-01, release date: 2008-04-29, Last modification date: 2024-05-29) |
| Primary citation | Zhang, Z.M.,Simmerman, J.A.,Guibao, C.D.,Zheng, J.J. GIT1 paxillin-binding domain is a four-helix bundle, and it binds to both paxillin LD2 and LD4 motifs. J.Biol.Chem., 283:18685-18693, 2008 Cited by PubMed: 18448431DOI: 10.1074/jbc.M801274200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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