2JWA
ErbB2 transmembrane segment dimer spatial structure
Summary for 2JWA
Entry DOI | 10.2210/pdb2jwa/pdb |
Descriptor | Receptor tyrosine-protein kinase erbB-2 (1 entity in total) |
Functional Keywords | transmembrane helix dimer, erbb2, protein kinase receptor membrane domain, atp-binding, glycoprotein, nucleotide-binding, phosphorylation, polymorphism, transferase, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: P04626 |
Total number of polymer chains | 2 |
Total formula weight | 9469.61 |
Authors | Mineev, K.S.,Bocharov, E.V.,Arseniev, A.S. (deposition date: 2007-10-09, release date: 2008-01-22, Last modification date: 2024-05-29) |
Primary citation | Bocharov, E.V.,Mineev, K.S.,Volynsky, P.E.,Ermolyuk, Y.S.,Tkach, E.N.,Sobol, A.G.,Chupin, V.V.,Kirpichnikov, M.P.,Efremov, R.G.,Arseniev, A.S. Spatial Structure of the Dimeric Transmembrane Domain of the Growth Factor Receptor ErbB2 Presumably Corresponding to the Receptor Active State J.Biol.Chem., 283:6950-6956, 2008 Cited by PubMed: 18178548DOI: 10.1074/jbc.M709202200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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