2JII
Structure of vaccinia related kinase 3
Summary for 2JII
Entry DOI | 10.2210/pdb2jii/pdb |
Descriptor | SERINE/THREONINE-PROTEIN KINASE VRK3 MOLECULE: VACCINIA RELATED KINASE 3, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | transferase, pseudo kinase domain, vaccinia related kinase, serine/threonine-protein kinase, vrk3, kinase, atp-binding, nucleotide-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus : Q8IV63 |
Total number of polymer chains | 2 |
Total formula weight | 80113.50 |
Authors | Bunkoczi, G.,Eswaran, J.,Pike, A.C.W.,Uppenberg, J.,Ugochukwu, E.,von Delft, F.,Cooper, C.,Salah, E.,Savitsky, P.,Burgess-Brown, N.,Keates, T.,Fedorov, O.,Sobott, F.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Weigelt, J.,Knapp, S. (deposition date: 2007-06-28, release date: 2007-07-10, Last modification date: 2018-02-28) |
Primary citation | Scheeff, E.D.,Eswaran, J.,Bunkoczi, G.,Knapp, S.,Manning, G. Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site. Structure, 17:128-138, 2009 Cited by PubMed: 19141289DOI: 10.1016/j.str.2008.10.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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