2JI7

X-ray structure of Oxalyl-CoA decarboxylase with covalent reaction intermediate

Summary for 2JI7

• Entry DOI: 10.2210/pdb2ji7/pdb
• Related: 2C31 2JI6 2JI8 2JI9 2JIB
• Descriptor: OXALYL-COA DECARBOXYLASE, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1R,11R,15S,17R)-19-[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]-1,11,15,17-TETRAHYDROXY-12,12-DIMETHYL-15,17-DIOXIDO-6,10-DIOXO-14,16,18-TRIOXA-2-THIA-5,9-DIAZA-15,17-DIPHOSPHANONADEC-1-YL}-5-(2-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: lyase, flavoprotein, decarboxylase, oxalate degradation, intermediate complex, thiamin diphosphate-dependent, thiamine pyrophosphate, non- oxidative decarboxylase
• Biological source: OXALOBACTER FORMIGENES
• Total number of polymer chains: 2
• Total formula weight: 126838.81

Authors

Berthold, C.L.,Toyota, C.G.,Moussatche, P.,Wood, M.D.,Leeper, F.,Richards, N.G.J.,Lindqvist, Y. (deposition date: 2007-02-26, release date: 2007-07-17, Last modification date: 2023-12-13)

• Primary citation: Berthold, C.L.,Toyota, C.G.,Moussatche, P.,Wood, M.D.,Leeper, F.,Richards, N.G.J.,Lindqvist, Y.; Crystallographic Snapshots of Oxalyl-Coa Decarboxylase Give Insights Into Catalysis by Nonoxidative Thdp-Dependent Decarboxylases; Structure, 15:853-, 2007; PubMed: 17637344; DOI: 10.1016/J.STR.2007.06.001

Experimental method

X-RAY DIFFRACTION (1.82 Å)