2JC9
Crystal structure of Human Cytosolic 5'-Nucleotidase II in complex with adenosine
Summary for 2JC9
Entry DOI | 10.2210/pdb2jc9/pdb |
Related | 2J2C |
Descriptor | CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | cytosolic 5-prime nucleotidase ii, gmp-imp specific nucleotidase, cn-ii, nt5c2, hydrolase, polymorphism, cytosolic purine 5-prime nucleotidase, allosteric enzyme, high km 5-prime nucleotidase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: P49902 |
Total number of polymer chains | 1 |
Total formula weight | 65312.22 |
Authors | Wallden, K.,Stenmark, P.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg, S.L.,Hogbom, M.,Karlberg, T.,Kotenyova, T.,Magnusdottir, A.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Thorsell, A.G.,Van Den Berg, S.,Loppnau, P.,Weigelt, J.,Welin, M.,Nordlund, P. (deposition date: 2006-12-21, release date: 2007-01-02, Last modification date: 2023-12-13) |
Primary citation | Wallden, K.,Stenmark, P.,Nyman, T.,Flodin, S.,Graslund, S.,Loppnau, P.,Bianchi, V.,Nordlund, P. Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition J.Biol.Chem., 282:17828-, 2007 Cited by PubMed: 17405878DOI: 10.1074/JBC.M700917200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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