2JAB
A designed ankyrin repeat protein evolved to picomolar affinity to Her2
Summary for 2JAB
Entry DOI | 10.2210/pdb2jab/pdb |
Descriptor | H10-2-G3 (2 entities in total) |
Functional Keywords | her2, darpin, ankyrin repeat protein, membrane protein, human epidermal growth factor receptor 2, de novo protein |
Biological source | SYNTHETIC CONSTRUCT |
Total number of polymer chains | 3 |
Total formula weight | 43855.31 |
Authors | Zahnd, C.,Wyler, E.,Schwenk, J.M.,Steiner, D.,Lawrence, M.C.,McKern, N.M.,Pecorari, F.,Ward, C.W.,Joos, T.O.,Pluckthun, A. (deposition date: 2006-11-27, release date: 2007-05-08, Last modification date: 2023-12-13) |
Primary citation | Zahnd, C.,Wyler, E.,Schwenk, J.M.,Steiner, D.,Lawrence, M.C.,Mckern, N.M.,Pecorari, F.,Ward, C.W.,Joos, T.O.,Pluckthun, A. A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2 J.Mol.Biol., 369:1015-, 2007 Cited by PubMed: 17466328DOI: 10.1016/J.JMB.2007.03.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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