2IOA

E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and ADP and phosphinate inhibitor

Summary for 2IOA

Entry DOI	10.2210/pdb2ioa/pdb
Related	2IO7 2IO8 2IO9 2IOB
Descriptor	Bifunctional glutathionylspermidine synthetase/amidase, MAGNESIUM ION, D-GAMMA-GLUTAMYL-N-{[(R)-{4-[(4-AMINOBUTYL)AMINO]BUTYL}(PHOSPHONOOXY)PHOSPHORYL]METHYL}-D-ALANINAMIDE, ... (5 entities in total)
Functional Keywords	bifunctional glutathionylspermidine synthetase/amidase, ligase, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	143209.99
Authors	Pai, C.H.,Chiang, B.Y.,Ko, T.P.,Chou, C.C.,Chong, C.M.,Yen, F.J.,Coward, J.K.,Wang, A.H.-J.,Lin, C.H. (deposition date: 2006-10-10, release date: 2006-12-12, Last modification date: 2024-03-13)
Primary citation	Pai, C.H.,Chiang, B.Y.,Ko, T.P.,Chou, C.C.,Chong, C.M.,Yen, F.J.,Chen, S.,Coward, J.K.,Wang, A.H.-J.,Lin, C.H. Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase Embo J., 25:5970-5982, 2006 Cited by PubMed: 17124497 DOI: 10.1038/sj.emboj.7601440 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation